Tetracycline antibiotics are broad-spectrum antibiotics in use since the 1940s. Older tetracycline-class antibiotics have been linked to cosmetic staining of permanent teeth when used in children before the age of 8 years. As a result, in 1970 a warning label was attached to all tetracycline-class antibiotics advising against the use in children under the age of 8 years. In 1967 doxycycline was introduced as a newer tetracycline-class antibiotic. Doxycycline binds less readily to calcium and has not been shown to cause the same tooth staining. Several studies have previously been published showing the lack of staining of permanent teeth when doxycycline was used in children. The warning, currently present on all tetracycline-class antibiotics, including doxycycline, continues to mention the concern regarding dental staining. If you need urgent medical help, call triple zero immediately healthdirect Australia is a free service where you can talk to a nurse or doctor who can help you know what to do.
Revised: 11 June 2015 This leaflet answers some common questions about DOXY tablets. It does not take the place of talking to your doctor and pharmacist. Your doctor weighed the risks of you taking DOXY tablets against the benefits this medicine is expected to have for you. Doxycycline belongs to a class of medicines called tetracyclines . If you have any concerns about taking this medicine, ask your doctor or pharmacist. These medicines work by killing or stopping the growth of bacteria which cause infection. It is used to treat infections of the: DOXY tablets may be used to aid medicines such as amoebicides (used to treat parasites). This means it can be used to treat a wide range of organisms. DOXY tablets may also be used to treat severe acne. DOXY tablets are only used to treat infections that will respond to it. Some infections are resistant to the effects of doxycycline. Your doctor may have prescribed DOXY tablets for another reason. In addition to the general indications for all members of the tetracycline antibiotics group, doxycycline is frequently used to treat Lyme disease, chronic prostatitis, sinusitis, pelvic inflammatory disease, Moraxella catarrhalis, Brucella melitensis, Chlamydia pneumoniae, and Mycoplasma pneumoniae are generally susceptible to doxycycline, while some Haemophilus spp., Mycoplasma hominis, and Pseudomonas aeruginosa have developed resistance to varying degrees. Some Gram-positive bacteria have developed resistance to doxycycline. Up to 44% of Streptococcus pyogenes and up to 74% of S. faecalis specimens have developed resistance to the tetracycline group of antibiotics. When bacteriologic testing indicates appropriate susceptibility to the drug, doxycycline may be used to treat these infections caused by Gram-positive bacteria: The World Health Organization Guidelines states that the combination of doxycycline with either artesunate or quinine may be used for the treatment of uncomplicated malaria due to Plasmodium falciparum or following intravenous treatment of severe malaria. Doxycycline kills the symbiotic Wolbachia bacteria in the reproductive tracts of parasitic filarial nematodes, making the nematodes sterile, and thus reducing transmission of diseases such as onchocerciasis and elephantiasis. Doxycycline has been used successfully to treat sexually transmitted, respiratory, and ophthalmic infections.
Doxycycline is an antibiotic drug that kills a wide, weird and wonderful range of bugs that are often difficult to treat with other antibiotics. These include bacteria and parasites that take up residence inside our cells (called “intracellular organisms”), making them hard for most antibiotics to reach. Unlike many other antibiotics, doxycycline penetrates deep into our tissues and ends up inside our cells, where it can kill these bugs. Examples of intracellular organisms susceptible to doxycycline include numerous “zoonotic infections” (infections that are spread from animals to humans), chlamydia, legionella (the cause of legionnaire’s disease) and malaria. Other susceptible microorganisms include “spirochaetes” (that can cause syphilis and Lyme disease) and the bacteria that cause acne, anthrax and cholera. Doxycycline interferes with a microorganism’s ability to manufacture proteins – the “building blocks” of life. Protein manufacture occurs in a part of the cell called the “ribosome” and is fundamental to any organism’s survival. Doxycycline has been found clinically effective in the treatment of a variety of infections caused by susceptible strains of Gram-positive and Gram-negative bacteria and certain other micro- organisms. Urinary tract infections Infections caused by susceptible strains of Klebsiella species, Enterobacter species. Respiratory tract infections Pneumonia and other lower respiratory tract infections due to susceptible strains of Streptococcus pneumoniae, Haemophilus influenzae, Klebsiella pneumoniae and other organisms. Escherichia coli, Streptococcus faecalis and other organisms. Sexually transmitted diseases Infections due to Chlamydia trachomatis including uncomplicated urethral, endocervical or rectal infections. Non-gonococcal urethritis caused by Ureaplasma urealyticum (T-mycoplasma). Doxycycline is also indicated in chancroid, granuloma inguinale and lymphogranuloma venereum. Doxycycline is an alternative drug in the treatment of gonorrhoea and syphilis. Dermatological infections Acne vulgaris when antibiotic therapy is considered necessary.
Feb 12, 2019. Doxycycline is an antibiotic used to treat bacterial infections, such as of the chest, sinus, eye and pelvic infections. It may be chosen if you are. In a recent study, experts at the CDC and Indian Health Service IHS found that short courses of the antibiotic doxycycline can be used in children without.