Editors carefully fact-check all Drugwatch content for accuracy and quality. The company’s first blockbuster drug was the numbing agent lidocaine, developed in 1948. This includes peer-reviewed medical journals, reputable media outlets, government reports, court records and interviews with qualified experts. UK-based drug company Astra Zeneca focuses on drugs that treat Type 2 diabetes, cancer and respiratory issues. This includes peer-reviewed medical journals, reputable media outlets, government reports, court records and interviews with qualified experts. But in the 2000s, it faced a number of scandals and litigation over its antipsychotic Seroquel. With more than 50,000 employees and $23 billion in revenue in 2016, the Cambridge-based company continues to rank among the largest drug companies in the world. Food and Drug Administration (FDA) approved its new bladder cancer drug, Imfinzi (durvalumab). Editors carefully fact-check all Drugwatch content for accuracy and quality. Formed by the merger of two companies, Astra AB and Zeneca Group PLC in 1999, the company had early success with drugs like the pain-numbing agent lidocaine. According to analysts, the drug could make $6.5 billion. But Astra Zeneca also had its share of legal trouble, paying more than $1 billion in federal fines and legal settlements for corrupting clinical trials and illegally promoting antipsychotics. It also faces several lawsuits filed by patients who say the drugmaker’s products injured them. Pradaxa® has been linked to serious bleeding events, heart attack and death. Read More It is believed that Zoloft® may increase the risk of serious birth defects in infants who are exposed during fetal development. Read More Despite being an effective contraceptive medication, Yaz® has been found to cause a range of mild to severe side effects.
The widely-prescribed cholesterol-lowering drug Crestor (generic: rosuvastatin) has been increasingly linked to cases of life-threatening muscle damage, heart injury, and kidney failure. Considering the severity of these potential side effects, the consumer watchdog group Public Citizen has petitioned for Crestor to be recalled nationwide. Food & Drug Administration (FDA) issued a press release today informing healthcare professionals of updates to the prescribing information concerning adverse interactions between protease inhibitors and certain statin medications. Food & Drug Administration (FDA) issued a press release today stating that it will be requiring all statin drugs to carry a new warning about the increased risk of elevated blood sugar and possible transient memory and cognition problems. The group cited too few clinical trials, the potential for numerous adverse complications, and the fact that Crestor has not been shown to lower the number of heart attacks and strokes, while three other similar statins have shown this benefit without the risk. When these two types of drugs are taken together, they may raise the blood levels of statins and increase the risk of a severe muscle injury known as myopathy. The label changes will apply to atorvastatin (Lipitor), fluvastatin (Lescol), lovastatin (Mevacor), lovastatin extended-release (Altoprev), pitavastatin (Livalo), pravastatin (Pravachol), rosuvastatin (Crestor), simvastatin (Zocor), and Advicor. Manufactured and marketed by Astra Zeneca, Crestor is an FDA-approved statin medication designed to work by blocking the production of cholesterol in the body. Crestor reduces levels of ‘bad’ cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood, while simultaneously increasing levels of ‘good’ cholesterol (high-density lipoprotein, or HDL). The drug is approved to treat high cholesterol in adults and children who are at least 10 years old. Lowering cholesterol levels can help prevent heart attacks, strokes, and vascular disease. Crestor has been linked to kidney damage and kidney failure. On October 22, 2004, the consumer group Public Citizen said twenty-nine patients who took Astra Zeneca’s cholesterol drug Crestor developed kidney damage. Crestor has also been linked to the potentially fatal disease Rhabdomyolysis. Consumer group, Public Citizens states, the rate of reported kidney problems is approximately 75 times higher with Crestor than with all other drugs in the same class combined. According to its analysis, there have been 6.4 reports of acute kidney failure or kidney damage for every 1 million Crestor prescriptions filled. Crestor has been linked to numerous cases of Rhabdomyolysis, a rare muscle destroying disease. Crestor is in the popular family of cholesterol-lowering drugs called Statins.
Did you know these deadly side effects were evident before Crestor was approved by the Food and Drug Administration? That's right, Crestor was approved by the Food and Drug Administration approval in August 2003, after a delay because of safety concerns. During FDA studies seven cases of the potentially fatal, muscle-destroying condition rhabdomyolysis occurred. These studies also linked Crestor with cases of kidney abnormalities not seen with other statins. The FDA decided to approve Crestor but at lower dosages. However, records from the FDA and health agencies in Canada and Britain show life-threatening side effects occur even at those lower doses. Similar to another statin cholesterol drug, Baycol, which was removed from the market, Crestor (Rosuvastatin Calcium) can cause or contribute to causing rhabdomyolysis, a condition in which muscle cells are damaged causing release of myoglobin, which in turn causes kidney damage and can be fatal. In August 2003, the Food and Drug Administration (FDA) approved Crestor as a cholesterol-reducing drug. Together with a low-cholesterol diet and exercise program, Crestor (or the generic version "rosuvastatin calcium") is supposed to reduce the level of bad cholesterol in your blood stream, and in some cases may also raise your good cholesterol levels. However, there have been reports that people taking Crestor have developed certain serious conditions, including the following: Many patients who experienced these conditions have filed Crestor lawsuits against the maker of the drug. Read on to learn more about the issues surrounding Crestor and how to receive compensation for injuries caused by the drug. Crestor Side Effects and Recall Several consumer groups asked the FDA to recall Crestor due in part to the reported serious side effects that arose after Crestor's approval. These groups cited cases where patients developed kidney failure or muscle damage (rhabdomyolysis) while taking the approved doses of Crestor. One 39-year-old woman even died of these conditions; and in studies prior to Crestor's approval, seven other people became ill with rhabdomyolysis.
Lipitor Class Action Lawsuit Claims & Attorney Settlements Millions of people across the United States suffer from high cholesterol levels, and there are many causes for this condition. Some people simply do not have genetics working in their favor while others don’t eat a healthy diet. Bad Drug Cases - Lawsuit Settlement News Mass Tort Services LLC. However, cases with serious injuries or death were settled at ranges above $200K. Birth Control Products Yaz, Yasmin, Ocella, Mirena, NuvaRing; Chantix; Crestor.