To comply with Canadian International Pharmacy Association regulations you are permitted to order a 3-month supply or the closest package size available based on your personal prescription. Talk to your pediatrician regarding the use of this medicine in children. Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. read more SILDENAFIL (sil DEN a fil) is used to treat pulmonary arterial hypertension. This medicine helps to improve symptoms and quality of life. Take your doses at regular intervals about 4 to 6 hours apart. Also tell them if you smoke, drink alcohol, or use illegal drugs. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. Tell your doctor or health care professional right away if you have any change in your eyesight or hearing. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. They need to know if you have any of these conditions: -anatomical deformation of the penis, Peyronie's disease, or history of priapism (painful and prolonged erection) -bleeding disorders -eye disease, vision problems -heart disease -high or low blood pressure -history of blood diseases, like sickle cell anemia or leukemia -kidney disease -liver disease -pulmonary veno-occlusive disease (PVOD) -stomach ulcer -an unusual or allergic reaction to sildenafil, other medicines, foods, dyes, or preservatives -pregnant or trying to get pregnant -breast-feeding Take this medicine by mouth with a glass of water. Do not stand or sit up quickly, especially if you are an older patient. Avoid alcoholic drinks; they can make you more dizzy. Do not take this medicine with any of the following medications: -cisapride -cobicistat -nitrates like amyl nitrite, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin -riociguat -telaprevir This medicine may also interact with the following medications: -antiviral medicines for HIV or AIDS -bosentan -certain medicines for benign prostatic hyperplasia (BPH) -certain medicines for blood pressure -certain medicines for fungal infections like ketoconazole and itraconazole -cimetidine -erythromycin -rifampin This list may not describe all possible interactions. Side effects that you should report to your doctor or health care professional as soon as possible: -allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue -breathing problems -changes in vision -chest pain -decreased hearing -fast, irregular heartbeat -men: prolonged or painful erection (lasting more than 4 hours) Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome): -facial flushing -headache -nosebleed -trouble sleeping -upset stomach This list may not describe all possible side effects. Call your doctor for medical advice about side effects. Revatio PO: 5 mg or 20 mg 3 times daily, administered 4-6 hours apart IV: 2.5-mg or 10-mg bolus 3 times daily if patient is temporarily unable to take PO Recommended PO/IV dose not to be exceeded Adding Revatio to bosentan does not have any beneficial effect on exercise capacity Not to be prescribed to children (1-17 years) for pulmonary arterial hypertension (PAH); this recommendation against use is based on long-term clinical pediatric trial showing that children taking high doses had higher risk of death than children taking low doses and that low doses were not effective in improving exercise ability (see Cautions) Elicits vasodilatory properties, resulting in mild and transient decreases in blood pressure Use with caution in patients with anatomic deformation of penis (eg, angulation, cavernosal fibrosis, or Peyronie disease), conditions potentially predisposing to priapism (eg, sickle cell anemia, multiple myeloma, or leukemia), cardiovascular disease, bleeding disorders, active peptic ulcer disease, liver disease, renal impairment, multidrug antihypertensive regimens, retinitis pigmentosa, concomitant use of CYP3A4 inhibitors Pulmonary vasodilators may significantly worsen cardiovascular status of patients with pulmonary veno-occlusive disease Patient taking alpha blocker should be stabilized before starting phosphodiesterase (PDE)-5 inhibitor, which should be initiated at lowest dose; if patient is already taking optimized dose of PDE-5 inhibitor, alpha blocker should be initated at lowest dose to avoid hypotension Not to be taken with other PDE-5 inhibitors Sudden decrease or loss of hearing, which may be accompanied by tinnitus and dizziness Viagra: Patients should stop sildenafil and seek medical care if a sudden loss of vision occurs in 1 or both eyes, which could be a sign of nonarteritic anterior ischemic optic neuropathy (NAION); use with caution, and only when the anticipated benefits outweigh the risks, in patients with a history of NAION; patients with a ”crowded” optic disc may also be at an increased risk of NAION; advise patients to seek immediate medical attention in the event of a sudden loss of vision Viagra: Potential for cardiac risk with sexual activity in patients with preexisting cardiovascular disease; therefore, treatment for erectile dysfunction generally should not be instituted in men for whom sexual activity is inadvisable because of their underlying cardiovascular status May cause dose-related impairment of color discrimination; use caution in patients with retinitis pigmentosa Evaluate underlying causes of erectile dysfunction or BPH before initiating therapy Revatio: In small, prematurely terminated study of patients with PAH secondary to sickle-cell disease, vaso-occlusive crises requiring hospitalization were more commonly reported by patients who received sildenafil than by those randomized to placebo; effectiveness of sildenafil in PAH secondary to sickle-cell anemia has not been established; the clinical relevance to men treated for erectile dysfunction with sildenafil is not known Revatio: Not for use in children with PAH; increased mortality with increasing doses (hazard ratio 3.5) was observed in randomized, double-blind, placebo-controlled clinical trial of 234 children (1-17 years) with PAH who had mild-to-moderate symptoms at baseline Revatio: Epistaxis occurred in 13% of patients with PAH secondary to connective tissue disease (eg, scleroderma); this effect was not seen in idiopathic PAH; incidence was also higher in those receiving concomitant PO vitamin K antagonist therapy (9%) than in those not receiving such therapy (2%) Limited published data from randomized controlled trials, case-controlled trials, and case series do not report a clear association with sildenafil and major birth defects, miscarriage, or adverse maternal or fetal outcomes when sildenafil is used during pregnancy; there are risks to mother and fetus from untreated pulmonary arterial hypertension Pregnant women with untreated pulmonary arterial hypertension are at risk for heart failure, stroke, preterm delivery, and maternal and fetal death Limited published data from a case report describe presence of sildenafil and its active metabolite in human milk; there is insufficient information about effects of sildenafil on breastfed infant and no information on effects of sildenafil on milk production; limited clinical data during lactation preclude a clear determination of risk of drug to an infant during lactation The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.
Revatio. GENERIC NAMES Sildenafil Antihypertensive Read Reviews 24. One product that may interact with this drug is riociguat. Sildenafil can cause a serious drop in your blood pressure. Revatio® is only available as a round, white 20 mg pill, to distinguish it from Viagra®, which is a blue diamond-shaped pill. Revatio® injection is supplied as a single-use vial containing 10 mg 12.5 mL of sildenafil.